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Mega-winners remain relatively rare, but they can and do happen. You just have to have enough guts to trust your hunch and buy stocks that few others are interested in.
Most investors understand that investing in stocks isn’t a get-rich-quick endeavor. Although the market is the most reliable and rewarding means of using capital to build real wealth, it can take years — even decades — to fully reap those rewards.
Sometimes, though, a ticker simply takes flight, dishing out enormous gains in a surprisingly short period of time. In some cases, they’ll even quadruple or quintuple your investment (if not more) in a matter of weeks. While this certainly isn’t the norm, it’s still worth a closer look to see what lit a fire under these names, and maybe figure out if these tickers can repeat the feat, or identify related stocks that may be about to do the same.
To this end, here’s a closer look at five of this year’s most rewarding names. Had you invested $5,000 in each of them at the beginning of the year, you’d be sitting on more than $136,000 today.

Image source: Getty Images.
1. Oklo
If this year will be remembered for anything (other than the ongoing proliferation of artificial intelligence, or AI), 2025 may well be remembered as the year that nuclear power became marketable again. The world needs more electricity, and it needs it now. It can’t wait for clean alternative energy sources to be built and come online, though. Nuclear is proven, and ready to go.
That’s what Oklo (OKLO 6.54%) brings to the table, but with an important twist.
Like NuScale Power, Kairos Power, and a handful of others, Oklo is working on small modular reactors with a small footprint that can be built and operated near where their power is consumed. Unlike Kairos, NuScale, and their peers, though, Oklo’s fast-neutron reactor design is not only far more efficient than more traditional water-cooled nuclear power plants, but can even be powered by used nuclear fuel (including its own). Its reactors are also safer, since their default status is simply to slow the reaction down if it grows too hot.
Oklo stock is up 631% this year, despite its recent lull.
2. Centrus Energy
Oklo isn’t the only stock to soar in 2025 due to the rekindled interest in nuclear power. Centrus Energy (LEU -1.99%) is up 517% for the same reason.
Well, not quite the exact same reason. Whereas Oklo designs and manufactures nuclear power technology, Centrus finds the fuel needed to make them work. Last year, it sold $442 million worth of uranium, up 38% year over year. And that’s despite a sizable setback in uranium prices over the course of 2024.
Analysts expect this profitable company to report revenue of $462 million this year, followed by a top line of $506 million in 2026, boosted by the renewed growth of the nuclear power industry.
3. Opendoor Technologies
To say it’s been an up-and-down year for real estate and its related stocks would be a considerable…
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Read More: Investing $5,000 in Each of These 5 Stocks at the Start of 2025 Would Have


